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More importantly, an orthostatic vitals test may confirm a suspected dysautonomia without the use of expensive diagnostic testing

However, because this was a retrospective observational study, the findings cannot establish that higher semaglutide doses directly caused the improved cardiovascular outcomes, and unmeasured confounding factors may have influenced the observed associations

Abstract Despite advances in therapies targeting hemodynamic and neurohormonal axes in heart failure (HF), incomplete reverse remodeling (RR) characterized by persistent myocardial edema and fibrosis remains a major clinical challenge