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TB-500 acts as an actin-binding protein that inhibits the polymerization of globular actin (G-actin) into filamentous actin (F-actin) and alters the cellular cytoskeleton [33, 34]

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In contrast to arthritis, the tenderness is in the muscles and tendons, not the bones or joints

By integrating molecular docking and network pharmacology approaches, we aim to enhance treatment efficacy and improve the quality of life for patients with AD