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For people who stop their GLP-1 medication, a second round of telogen effluvium can sometimes occur as the body readjusts to increased caloric intake and changing hormonal signals

The peptide functions as a precision senolytic agent by competing with endogenous FOXO4 for p53 binding, releasing the tumor suppressor protein to trigger apoptosis specifically in cells that have accumulated the senescence-associated secretory phenotype (SASP) markers

During the treatment period of three weeks, mice were monitored daily for food intake and body weight (Fig

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