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Targeting arginine metabolism pathway to treat arginine-dependent cancers

Signs it might be legitimate remodelling: Mild, diffuse changes in the first 2-4 weeks

A pivotal role for endogenous TGF--activated kinase-1 in the LKB1 AMP-activated protein kinase energy-sensor pathway

Although few studies have evaluated the expression of KP metabolites in postmortem samples, TDO protein expression was elevated in white matter glial cells in the anterior cingulate gyrus in samples from MDD patients [61], potentially contributing to localized neuroinflammation