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Emodin suppresses cancer progression via classical modalities Emodin, a versatile natural compound, exerts its antitumor effects through multiple mechanisms, including cell cycle arrest, apoptosis induction, angiogenesis inhibition, migration, and invasion suppression and tumor metastasis inhibition in NSCLC, breast, ovarian, endometrial, liver, cervical, colon, endometrial cancers, as well as melanoma, and papillary thyroid carcinoma [448, 460]

Newborns are often exposed to oxygen therapies, have low antioxidant defenses despite high levels of toxic radicals, and are more susceptible to infections, especially if born prematurely 99

DOI: 10.1038/nrn1583 Schwartz M et al (1990): Oral nifedipine in the treatment of hypertensive urgency: cerebrovascular accident following a single dose

In Western populations, pediatric AIH often presents as an acute hepatitis-like illness resembling viral hepatitis