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Fangchinoline inhibits non-small cell lung cancer metastasis by reversing epithelial-mesenchymal transition and suppressing the cytosolic ROS-related Akt-mTOR signaling pathway

The effects exerted by pro-inflammatory cytokines on muscle mass are partially mediated by the induction of the transcription factor NF-B signalling [48, 76, 77]

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

To date, few radiosensitising drugs have been approved for use clinically ( in vitro and ex vivo models of oesophageal adenocarcinoma ( Metformin is a clinically approved drug used for the management of type II diabetes ( This study demonstrates, through real-time live cell metabolic profiling and transcriptomic profiling, that metformin significantly alters energy metabolism in both in vitro and ex vivo models of rectal adenocarcinoma and importantly, radiosensitises radioresistant rectal cancer cells to clinically-relevant doses of X-ray radiation