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ESI-MS (m/z): [M + H] + Calcd for C 16 H 18 N + :224.14

2, 7-dichlrodihydro-fluorescein-diacetate(H2DCF-DA) and MitoSOX Red were used to detect cellular and mitochondrial levels of ROS

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Second, selective inhibition of mTORC1, without concurrent suppression of mTORC2, triggers compensatory activation of the PI3KAKT pathway via an S6K1IRS1 feedback loop, promoting cell survival rather than suppression