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Optimising product ergonomics, usability, and risk management is essential when integrating various components within patient-operated devices, which ensures both user safety and regulatory adherence [65]

These include hydrophobic attraction of nonpolar side chains in contact regions of the subunits, electrostatic interactions between ionic groups of opposite charge: hydrogen bonds between polar groups

Enforced expression of SLC27A5 contributed to the upregulation of genes promoting lipid peroxidation and dysregulation of iron homeostasis (Figs