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Tesamorelin is FDA-approved (narrowly)

Neuroinflammation, which has emerged as a crucial cause of cognitive dysfunction, such as Alzheimers Disease, could be caused through inflamed adipose tissue of obesity (53)

Hoboken, NJ: John Wiley & Sons, Inc, 5370

In HCC33 and H82, in which TXNRD1 inhibition induced high levels of hydrogen peroxide (H 2 O 2 ) and hydroxyl radical (OH), the iron/copper chelator deferoxamine (DFO) strongly reduces cell death, presumably by preventing the formation of toxic levels of OH