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For example, METTL16 lactylation promotes cuproptosis in gastric cancer, whereas METTL3-induced m6A RNA modifications in colorectal tumors highlight the regulatory role of lactate in immune responses [113, 114]

Therefore, it is recommended that patients with ADH-D should be counseled on the importance of maintaining their desmopressin therapy and adequate hydration, increasing fluid intake when consuming alcohol, and recognizing symptoms of dehydration or hypernatremia (e.g., thirst, dry mouth, dizziness) to minimize the risk of dehydration and electrolyte imbalance