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10.1016/j.biopha.2022.113888 182 ZhangX.DengF.WangX.LiuF.ZhuY.YuB.et al (2024a)

We observed that sUA also activates the NLRP3 inflammasome through ion flux, specifically via potassium efflux, since the inhibition of cellular K + removal in WT macrophages also inhibited IL-1 production (Sup