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Recall that Shc ultimately activates the MAPK pathway, while PLC has more metabolic effects including GLUT4 translocation

Xu R, Stalter RM, Doubleday A, et al

Pilon-Smits, 2019)], demonstrating that plants have the genetic capability to serve as a valuable Se dietary source

doi: Dong Y, Wang H, Chen Z (2015) Alpha-lipoic acid attenuates cerebral ischemia and reperfusion injury via insulin receptor and PI3K/Akt-dependent inhibition of NADPH oxidase