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Copper tripeptide-1 is made up of two different compounds, GHK and Cu

Hormone and Metabolic Research, 47 (10), 721-726

when present, each R 6 is independently selected from (1) cyano, (2) halogen, (3) (C 1-6 )alkyl or OC 1-6 alkyl wherein the alkyl moiety is optionally substituted with cyano, (4) (C 3-6 )cycloalkyl, optionally substituted with halogen, C 1-6 alkyl, C 1-6 haloalkyl, cyano, OH or OC 1-6 alkyl, (5) C(O)N(R 1 ) 2 , (6) (C 3-6 )cycloalkyloxy wherein the cycloalkyl is optionally substituted with halogen, C 1-6 alkyl, C 1-6 haloalkyl, cyano, OH, or OC 1-6 alkyl, (7) hydroxy, (8) NR 11 R 11 , (9) (C 1-6 )haloalkyl-, (10) (C 1-6 )haloalkoxy-, (11) SO 2 (C 1-6 )alkyl, (12) SONH(C 1-6 )alkyl, (13) C 1-6 alkyl-NR 11 R 11 , or (14) 5 membered heteroaryl comprising 2 nitrogen atoms

Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor kappaB-mediated pathogenic pathways