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Reception [edit] Writing for The Guardian , Justine Jordan stated: "This is a sprawling, capacious novel, but expertly foreshadowed and so intricately put together that many throwaway moments only take on resonance on a second reading." She concluded : "You won't read a sadder, truer, funnier novel this year." [8] Writing for The New York Times , Jen Doll stated that Murray's writing is "pure joy - propulsive, insightful and seeding with hilarious observations." [9] Writing for The Los Angeles Times , author Jonathan Russell Clark called the novel "a triumph of realist fiction, a big, sprawling social novel in the vein of Jonathan Franzens 'Freedom.'" The review further stated: "The agility with which Murray structures the narrative around the family at its heart is virtuosic and sure-footed, evidence of a writer at the height of his power deftly shifting perspectives, style and syntax to maximize emotional impact

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In addition, altered plasma Gln levels [8,9,10] have been reported in ASD compared to controls

While the animal studies are intriguing, they are not a substitute for robust human data