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5.2.4 Age, genetics, and comorbidities Individual susceptibility to the neurotoxic effects of ketamine varies according to age, genetic factors, and comorbidities

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Initial clinical trials only tested a gap of less than six months between doses, but unexpected popularity and resulting shortages caused further testing to validate wider spacing of the two doses

Crucially, they demonstrated that Vitamin B12 supplementation successfully regulates this hyperinflammation through epigenetic mechanisms, showing immense promise for reversing Long COVID-induced neuroinflammation and cognitive decline