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As a critical coenzyme involved in numerous biological processes, NAD levels play a pivotal role in energy production, DNA repair, and cellular signalling pathways

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Pomegranate-derived compounds have been shown to modulate a wide range of molecular targets, including transcription factors, pro- and anti-apoptotic proteins, cell cycle regulators, protein kinases, cell adhesion molecules, pro-inflammatory mediators, and growth factors across multiple cancer types, such as skin, breast, prostate, colon, and lung cancers (366, 367)

This has led scientists to consider NGF as a potential biomarker for diagnosing and tracking depression, though its not widely used in clinical practice yet