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The Chemistry of Endogenous and Exogenous Reactive Oxygen Species Formation As previously observed, free radicals composed of oxygen are mainly formed by an electron transfer reaction through several pathways, with the main group of ROS being formed during natural biological processes in aerobic cells

The polynucleotide construct of the invention can be delivered to the interstitial space of tissues within the an animal, including of muscle, skin, brain, lung, liver, spleen, bone marrow, thymus, heart, lymph, blood, bone, cartilage, pancreas, kidney, gall bladder, stomach, intestine, testis, ovary, uterus, rectum, nervous system, eye, gland, and connective tissue

Cochrane Database Syst Rev (2011) 16:CD005228.10.1002/14651858.CD005228.pub3 25 GaripagaogluMKayikiogluFKseMFAdliMGlkesenKHKoakZet alAdding concurrent low dose continuous infusion of cisplatin to radiotherapy in locally advanced cervical carcinoma: a prospective randomized pilot study

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