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Oxidative Medicine and Cellular Longevity 2017 , 14, (2017)

HRMS (FAB+) calculated for C 16 H 24 N 2 O 2 : 418.2369

Low dose naltrexone (LDN) Naltrexone has the highest -opioid receptors affinity, like naloxone being pure opioid antagonist that was approved by FDA for the treatment of opioid addiction in 1984 [92]