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DOI:10.1016/j.ajpath.2014.12.017 30

Prevention Strategies: Adopt a calorie organized meal plan

Acylamino refers to the groups - R 30 C(O)alkyl, - R 30 C(O)substituted alkyl, R 30 is hydrogen or alkyl and wherein alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic are as defined herein

Activation of the upstream regulator peroxisome proliferator-activated receptor (PPAR) induces the expression of ferroptosis suppressor protein 1 while simultaneously downregulating APP synthesis and inhibiting -site APP cleaving enzyme 1 hydrolytic activity, effectively reducing A oligomer generation (121)