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Furthermore, selenium deficiency also downregulated proinflammatory arachidonic acid downstream lipid mediator leukotriene B4 (LTB 4 ) production in caprine neutrophils, another arachidonic acidderived ALOX product that promotes neutrophil chemotaxis [35]

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4.3 HIV co-infection and antiretroviral therapy HIV-positive individuals are at increased risk of parkinsonism due to basal ganglia vulnerability to viral neurotoxicity, chronic inflammation, and mitochondrial stress (Denaro et al., 2022

Supplemented as an additional push" at the end of the treatment to enhance cellular detoxification processes and potentially decrease overall oxidative stress burden