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APOE4 expression increases unsaturated triglyceride-rich lipid droplet formation in astrocytic endoplasmic reticulum (ER), impairing lipid droplet clearance and heightening sensitivity to lipid peroxidation, thereby elevating AD risk (Windham et al., 2024)

Developed by researchers at Washington State University, this synthetic peptide is designed to stimulate the growth of new synaptic connections in the brain, potentially making it one of the most powerful experimental cognitive enhancers to date

489 In T2DM, the role of glycemic control in preventing neuropathy is more complex

Aspartate rescues S-phase arrest caused by suppression of glutamine utilization in KRas-driven cancer cells