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A GLP-1 blocker acts by inhibiting the GLP-1 receptor, which modulates the downstream inflammatory pathways linked to: cytokine production immune system activation oxidative stress inflammatory signaling in tissues such as the liver, fat cells, and gut In low doses, blocking GLP-1 receptors appears to influence the immune system without significantly interfering with glucose control which is why this approach is being studied specifically for inflammation rather than metabolic disease

This work was supported by VA-merit BX002086 (to P.D.), DK088902 (to A.B.S.) and BX002761 (to A.B.S.)

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Yes the peptide protocol and physical therapy are complementary