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[1] [3] [7] [5] [9] [22] [16] :17 [23] [24] Diagnosis and diagnostic criteria Research papers have concluded that knowledge and education about MCS among health professionals is lacking and that this commonly results in delays in the diagnosis and poor management of the condition

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Moreover, this study revealed for the first time that the downregulation of the mitochondrial biogenesis coactivator PGC-1 and its downstream nuclear factors are linked to mtDNA content in high-fat diet-induced obesity, muscle density loss, mitochondrial and myocardial contractile dysfunction, ROS accumulation, and intracellular Ca 2+ signaling