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doi: 10.1002/hep.22159

Ketamine does more than prevent pain during surgery

It can attenuate activity of the NMDA receptor (Majewska et al., 1990), enhance the uptake of glutamate from the synaptic cleft (Lane and Lawen, 2013), and directly inhibit calcium channels, thereby modulating neuronal excitability (Nelson et al., 2007)