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By looking at a specific part of the brain called the globus pallidus, and comparing it to another area, researchers can see how much manganese is present.[60][84] Other tests, like PET scans, the use of a special type of MRI scan that can measure specific molecules in the brain, and tests of manganese and a protein called ferritin in the blood, have also been used to try to get a clearer picture of how much manganese is in the brain.[85][86][87] To sum it up, diagnosing manganese toxicity requires doctors to be on high alert, especially when theyre treating patients who have a higher risk of exposure

It is linked to mitochondrial biogenesis [Citation4]

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