Lyophilized GHK-Cu shelf life (before reconstitution) Freezer storage (-20C): 12-24 months Most common storage Standard home freezer adequate Expected shelf life: 18-24 months typical GHK-Cu slightly shorter than some peptides (copper oxidation) Still excellent storage option Why GHK-Cu shelf life shorter than some peptides: Contains copper (oxidation concern) Copper can catalyze degradation More sensitive than copper-free peptides But still stable for 1-2 years frozen Refrigerator storage (2-8C): 6-12 months Acceptable if using soon Shorter than freezer 6 months very safe 12 months likely fine but degradation starting Room temperature: Weeks to 2-3 months Not recommended for storage Only during shipping or brief periods Copper oxidation accelerates Use freezer or fridge GHK-Cu vs other peptides shelf life: Maximizing lyophilized GHK-Cu shelf life: Freeze immediately upon receipt Keep in sealed vial (moisture is enemy) Store in box (protect from light) Minimize freeze-thaw cycles Label with date received See our peptide storage guide , do peptides expire , and should copper peptides be refrigerated

10.1038/ajg.2013.451 [DOI] [PubMed] [Google Scholar] Atreya R., Mudter J., Finotto S., Mllberg J., Jostock T., Wirtz S., et al
Alternatively, use a vitamin C derivative like magnesium ascorbyl phosphate or sodium ascorbyl phosphate, which function at a higher pH and play much more nicely with copper peptides
Initial research focused on its role in wound healing and tissue remodeling, where it was found to modulate the expression of extracellular matrix (ECM) proteins such as collagen and elastin