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during tissue invasion, the conidia germinate into hyphae with loss of TLR4 stimulation, leading to a less pronounced stimulation of proinflammatory cytokines.53,199 TLR4-mediated proinflammatory effects have been demonstrated to be important in the protection against IA.28 Hence the tissue-invasive hypha of A

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Moreover, eriocitrin, a citrus-derived flavonoid, demonstrated significant reductions in glycemia, systemic inflammation, and oxidative stress, while also enhancing GLP-1 secretion in prediabetic individuals

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