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Nanaomycin A ( 64 ) is an antibiotic that was recently reported to selectively inhibit DNMT3B with an IC 50 of 500 nM, while the activity of DNMT1 was not affected (Figure 10)

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Recent advances in targeting ion channels to treat chronic pain

At the same time, our study suggests that using antioxidants as an adjuvant therapy strategy, as is done in chronic periodontitis (Castro et al., 2019), may reduce the biochemical changes caused or possibly interfere with the progression of apical periodontitis