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It is now believed that the long-term Mediterranean diet has a potential protective effect on cardiovascular diseases, stroke, obesity, diabetes, hypertension, malignant tumors, allergic diseases, as well as Alzheimers disease and Parkinsons disease (87)

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Cytokinergic IgE activity may provide a rationale for the paradoxical observation that the risk of developing an allergic disease and severity of the disease is more closely related to the levels of total IgE than allergen-specific IgE in serum (Burrows et al., Germinal Center Reactions and the Local B Cell Repertoire)