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Reported side effects Mild headache or fatigue typically transient during initial use Mild gastrointestinal discomfort reported in some oral formulation users Sleep disruption or irritability potential sign of overstimulation Theoretical safety concerns Critical note: Because Dihexa activates the HGF/c-Met pathway which promotes cellular growth and repair there is a theoretical concern that it could potentially stimulate unwanted cell proliferation in individuals with active cancer or high cancer risk

After incubation, cells were washed with PBS and left in warm serum-free media for imaging at a Zeiss LSM700 confocal microscope

The product is manufactured under USP and cGMP standards at Pfizer-operated facilities

The optical density (O.D.) at 450 nm minus the O.D