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Description

DUSP14 is induced in peripheral blood T cells of AS patients [77], but is reduced in the liver tissue of NAFLD patients [199] and the heart tissue of heart failure patients [235]

PMID 28621100

If GSH peroxidase activity is deficient, lipid peroxidation could increase in the tissues, leading to increased stimulation of PGH synthase, increased thromboxane production, and further increase lipid peroxides