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Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis

In insulin resistance, the body does not respond to the increasing insulin levels, therefore causing the excess glucose in the blood to be taken up by the liver and converted to fat, increasing overall fatty tissue

Methods: We generated liver-specific REG1 knockout (KO) mice, liver-specific REG1/Pten double KO (LDKO), hepatocyte-specific REG1/Pten double KO (HDKO), and cholangiocyte-specific REG1/Pten double KO (CDKO) mice, and crossed them with ROSA-LacZ mice for lineage tracing

The thymus, the organ responsible for educating immune T-cells, shrinks so dramatically with age that by the time most people reach their forties, it has been largely replaced by fat tissue, leaving the immune system relying on an aging, diminishing repertoire of cells [2]