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It was recently demonstrated that the CLAVATA3/EMBRYO-SURROUNDING REGION-RELATED25 (CLE25) peptide serves as a long-distance signal for the synthesis of ABA in leaves that is generated from the roots (Soma et al., 2020)

This was also associated with decreased Lsd1 and Lsd1+8a mRNA expression, decreased LSD1 protein expression, and decreased LSD1 binding to the Bdnf exon IV promoter, as well as increased anxiety-like behaviors and voluntary ethanol consumption (40)

Methods Human tumor tissues The human tissue study protocol was approved by the Ethics Committee of Fourth Military Medical University (Approval number KY20183305-l) and informed consents have been obtained from the participants

Since the minimum and maximum concentrations at which the effect of reducing opacity was observed were 5 mM and 40 mM, respectively, the analysis was performed at 20 mM, which is the concentration in the middle