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doi:10.2147/OTT.S121472 Chen P, Li C, Li X, Li J, Chu R, Wang H

The standard recommendation is 2 months on, 2 months off

126 Mechanistically, most interactions involve modulation of hepatic enzymes and transporters, which can lead to subtherapeutic effects or heightened toxicity depending on whether the herb acts as an enzyme inducer or inhibitor

EXTENDED DISCUSSION Biochemical and structural studies of GPX4 and its inhibitors have been hindered by the lack of an efficient source of wild-type GPX4 protein 5,49,50