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This process results in hemolysis, marked by elevated lactate dehydrogenase (LDH), increased indirect (unconjugated) bilirubin, and undetectable haptoglobin levels

GSH-activated prodrugs, including disulfide- and diselenide-linked conjugates, are selectively activated in tumors, enabling high drug loading and targeted delivery

Summary Keywords vitamin C, ascorbate, intravenous vitamin C, cancer, chemotherapy, pharmacokinetics, enzyme cofactor, quality of life Citation Carr AC and Cook J (2018) Intravenous Vitamin C for Cancer Therapy Identifying the Current Gaps in Our Knowledge

performed the behavioral and molecular experiments in rats with input from L.T