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Vegetarians should include fortified foods or supplements to meet daily B12 requirements

4.2.2 Chronic kidney injury and renal fibrosis One of the notable pathological characteristics of CKD is renal fibrosis, a prolonged wound-healing process that responds to multiple tissue injuries in the kidney

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Defects in cellular ATP production found in several regions of PD brains have been associated with mitochondrial dysfunction 71 , and previous studies showing that HPRT1 deficiency inhibits mitochondrial protein complex I-dependent respiration 72 indicate that HPRT1 may be involved in energy metabolism dysregulations in PD