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Description

OShea JJ, Schwartz DM, Villarino AV et al (2015) The JAK-STAT pathway: impact on human disease and therapeutic intervention

Research Protocol Considerations Note: The following describes published research methodology, not recommendations for any specific protocol

PMID: 28682832

Loss of GPX4 leads to uncontrolled lipid peroxidation with the highest levels of lipid peroxidation in immature reticulocytes when both GPX4 and vitamin E (known to antagonize peroxide production) were deficient ( LC3 lipidation