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In the transition metal chelation mechanism, polyphenol anions chelate heavy metals through the deprotonation of hydroxyl groups, forming metal complexes and releasing a proton (ArOH ArO + H+) (160)

ZarkovicNZarkovicKMilkovicLAndrisicLBorovicSWaegGet alRevealing 4-Hydroxynonenal-Histidine adducts as qualitative and quantitative biomarker of oxidative stress, lipid peroxidation and oxidative homeostasis

Natural Compounds That Modulate Nrf2 Pathways There has been a wealth of research looking at agents (naturally occurring and synthetic) that can upregulate this global antioxidant and detoxification system

Neither is better, but both are essential for good health and well-being