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Immune and Recovery Modulation Studies: In sleep-deprived rats and limited clinical observations, DSIP exhibited mild anti-inflammatory effects (reduced IL-6, TNF-), enhanced antioxidant enzyme activity (SOD, catalase), and accelerated physiological recovery from physical/psychological stress

Applying any pressure to your face, particularly your cheek or jawline

This is not a direct drug effect but rather a consequence of significant caloric deficit and rapid body changes

Constipation is the most frequent autonomic feature affecting PD individuals and is determined by both neurogenic and non-neurogenic factors, such as reduced mobility and abdominal muscle tone, a diet poor in fibers and insufficient fluid intake, all contributing to a prolonged gastrointestinal transit time and sometimes megacolon [251]