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The Centers for Disease Control and Prevention (CDC) and other authorities recommend methotrexate be administered only by healthcare professionals familiar with its uses, toxicities, and safety precautions

Importantly, functional B12 deficiency can sometimes coexist with high total B12 levels, especially in kidney disease, and may require additional testing with methylmalonic acid (MMA) or holotranscobalamin if deficiency is suspected clinically

While some people may experience noticeable benefits from MIC B12 injections, results can vary

These are the cells responsible for making intrinsic factor in the first place