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Enhanced preclinical antitumor activity of M7824, a bifunctional fusion protein simultaneously targeting PD-L1 and TGF-beta

BPC-157 acts primarily on the nitric oxide (NO) system , VEGF-mediated angiogenesis and gastric mucosal protection pathways central to vascular repair, tendon-to-bone healing, and gastrointestinal models

To address the need for independent validation, we systematically evaluated all lead variants in publicly available POAG GWAS datasets, including UK Biobank (European ancestry), POAAGG (African ancestry), and other published studies identified through the GWAS Catalog

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