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Because LaccID does not require H 2 O 2 and its activity is inherently selective for the cell surface (obviating the need for special probes such as BxxP), we wondered whether LaccID could be used for nontoxic mapping of cell-type-specific surfaceomes in complex biological settings

Meanwhile, p53 activation negatively regulates xCT, thereby increasing sensitivity to ferroptosis ( 6 Drugs targeting ferroptosis and intrinsic immunity for the treatment of DKD 6.1 Sodium-glucose cotransporter protein-2 inhibitor Sodium-glucose cotransporters (SGLTs) are transmembrane proteins crucial for transporting sodium ions and glucose (264)

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Structural and regulatory pathway interaction