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is a scientific advisor to Third Rock Ventures and Nereid Therapeutics

In particular, a peptide inhibitor of JNK kinase-mediated mitochondrial cell death pathway, D-JNKI-1 peptide, has shown promises in protecting the cochlea against noise-induced and aminoglycoside induced HC loss when delivered directly into the scala tympani or locally to the round window membrane (Wang et al., 2003b, 2007

Epithelial cellextracellular matrix interactions and stem cells in airway epithelial regeneration

It can competitively inhibit MET channels, thereby reducing gentamicin uptake into hair cells, and may also interfere with prestin function, indirectly mitigating the toxic effects on cochlear amplification