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Description

Adipocytes, which act as glucose sensors [145], senses impaired GLUT4-mediated glucose uptake and release adipocytokines (such as retinol-binding protein 4, RBP 4) to prevent glucose uptake by skeletal muscle and improve hepatic glucose output through insulin signalling blockade [146]

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Recent studies have highlighted that CD8 + T cells exhibit selective depletion in the duodenum of patients with ALD, resulting in compromised intestinal barrier function and exacerbation of ALD pathology

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