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Beyond mortality: exploring the influence of plant phenolics on modulating ferroptosisa systematic review

doi: 10.1038/s41423-024-01220-3 117 CaoQWangYChenJWangRChenTGlossBet al

doi:10.1001/jamanetworkopen.2020.36304

This system uses TrxR to reduce Trx with NADPH, which maintains the reduced state of intracellular proteins through disulfide bond exchange, thereby maintaining cell survival in the event of a GPX4 functional defect (161)