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Both studies also reported relative safety and no side effects that may otherwise occur with exogenous hGH use [2]: No statistically significant differences in IGF-1 levels were observed among the treatment and placebo groups throughout the study

Better insulin sensitivity can help prevent and manage type 2 diabetes

Cancer history or active malignancy concerns need clinician review before GH-axis stimulation is considered

Daratumumab is approved as monotherapy and in combination with IMiD drugs (i.e., lenalidomide or pomalidomide based on the POLLUX, EQUULEUS, and APOLLO trials) or PIs (i.e., bortezomib or carfilzomib based on the CASTOR and CANDOR trials), plus dexamethasone for RRMM patients