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Similar content being viewed by others Introduction Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that manifests with inflammation and ulcers in the colonic lining, resulting in a spectrum of symptoms including abdominal pain, diarrhea, rectal bleeding, tenesmus (a sense of pressure), and weight loss [1, 2]

Similarly, activated microglia contribute to oxidative stress by upregulating NADPH oxidase 2 (NOX2), which generates O , and inducible nitric oxide synthase (iNOS), which produces nitric oxide (NO)

Melanomas with a thickness of 4mm would be considered thick and have a much worse prognosis (55% at 5 years)

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