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GH secretagogue was developed for therapy in osteoporosis and muscle wasting, but the official manufacturing of Ibutamoren was discontinued due to a lack of effectiveness in clinical studies

[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Ntasi G., Tsarbopoulos A., Mikros E., Gikas E

Effect of epitalon on lifespan and spontaneous tumor incidence in mice

While this acute effect has been studied primarily in the context of cardioprotection research, any acute hemodynamic modulation carries theoretical safety implications in research models involving compromised cardiovascular function