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Therefore, the diagnosis of PLPHP deficiency still relies on standard B6 testing and genetic testing

Breastfeeding Methylcobalamin is distributed into breast milk in amounts similar to those in maternal plasma, and distribution in breast milk allows for adequate intakes of methylcobalamin by breastfeeding infants

If overdose is suspected or if neurologic symptoms emerge, stop further dosing and seek medical evaluation

By reducing both the cleavage of caspase-3 itself and the cleavage of PARP, AHK-Cu appears to interfere with this terminal step in the apoptotic process