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Moreover, the knockout of Alox15 could not rescue GPX4-deficiency-induced ferroptosis in fibroblasts ( The mevalonate pathway includes the production of isopentenyl pyrophosphate, squalene, coenzyme Q10, and cholesterol, which affect ferroptosis

Evidence for the presence of L-arginine-nitric oxide pathway in human red blood cells: relevance in the effects of red blood cells on platelet function